Patagonia is a town in Santa Cruz County, Arizona, United States. According to 2006 Census Bureau estimates, the population of the town is 825. Patagonia was formerly a supply center for nearby mines and ranches. Currently, it is a tourist destination, retirement community and arts and crafts center. The Nature Conservancy's Patagonia-Sonoita Creek Preserve is adjacent. Patagonia apartments for rent comparison page shows most up to date rent information on Patagonia apartments and houses. Rent information is obtained from multiple rental sources but we cannot guarantee their accuracy.