Santa Ana is the most populous city in Orange County, California and is the county seat. It lies approximately 10 miles inland from the Pacific Ocean, on the largely seasonal Santa Ana River. The Santa Ana Freeway runs through the city, and the Costa Mesa Freeway and Garden Grove Freeway travel along its edges. It is today best-known for its enormous Hispanic population, now comprising over 75% of what was once a virtually all-white city. The current OMB metropolitan designation for Santa Ana and the Orange County Area is 'Santa Ana-Anaheim-Irvine, CA.' Santa Ana apartments for rent comparison page shows most up to date rent information on Santa Ana apartments and houses. Rent information is obtained from multiple rental sources but we cannot guarantee their accuracy.