La Mesa is a city in San Diego County, California, United States. The population was 54,749 at the 2000 census. It was founded in 1869 and officially incorporated as a city on February 16, 1912. It is the hometown of NBA legend Bill Walton. La Mesa apartments for rent comparison page shows most up to date rent information on La Mesa apartments and houses. Rent information is obtained from multiple rental sources but we cannot guarantee their accuracy.