Sanibel is a city in Lee County, Florida, United States. As of the 2000 census, the city had a total population of 6,064. As of 2004, the population recorded by the U.S. Census Bureau is 6,102. Sanibel apartments for rent comparison page shows most up to date rent information on Sanibel apartments and houses. Rent information is obtained from multiple rental sources but we cannot guarantee their accuracy.