Guthrie Center is a city in Guthrie County, Iowa, United States, along the South Raccoon River. The population was 1,668 at the 2000 census. It is the county seat of Guthrie County. Guthrie Center apartments for rent comparison page shows most up to date rent information on Guthrie Center apartments and houses. Rent information is obtained from multiple rental sources but we cannot guarantee their accuracy.