Natchez is the county seat and largest city within Adams County, Mississippi. As of the 2000 census, the city had a total population of 18,464. One of Mississippi's oldest cities, it was founded in 1716, predating the current capital city - Jackson - by more than a century. Located along the Mississippi River, Natchez is the southern terminus of the Natchez Trace Parkway. The city is famous in American history for its role in the development of the Old Southwest, particularly with respect to its location on the Mississippi River. Natchez apartments for rent comparison page shows most up to date rent information on Natchez apartments and houses. Rent information is obtained from multiple rental sources but we cannot guarantee their accuracy.