Buffalo is an American city in western New York. As of the 2000 census, the city had a total population of 292,648. It is the state's second-largest city, after New York City, and is the county seat of Erie County. It is also the economic and cultural center of the Buffalo-Niagara Falls metropolitan area, with a population of.2 million people, as well as being the dominant city of Western New York, a part of the broader Buffalo Niagara Region. The Buffalo area is adjacent to the Golden Horseshoe, an urban region in southern Ontario. Buffalo apartments for rent comparison page shows most up to date rent information on Buffalo apartments and houses. Rent information is obtained from multiple rental sources but we cannot guarantee their accuracy.