Greenville is a borough in Mercer County, Pennsylvania on the Shenango River, 72 miles north by west of Pittsburgh. It is the seat of Thiel College, opened in 1870. In the past, the manufacturing interests included railroad shops, bridge works, gristmills, a cement-block plant, an automobile factory, foundries and machine shops, saw and planing mills, steelworks, a railroad-car manufacturer, and flour mills. Good water power was supplied by the Shenango River. In 1900, 4,814 people lived in Greenville; the number rose to 5,909 in 1910; and stood at 10,000 in 1940. The population was 6,380 at the 2000 census. Greenville apartments for rent comparison page shows most up to date rent information on Greenville apartments and houses. Rent information is obtained from multiple rental sources but we cannot guarantee their accuracy.