Big Spring is a city located in the U.S. state of Texas at the crossroads of U.S. Highway 87 and Interstate 20; its population of 25,233 makes it the largest city between Midland to the west, Abilene to the east, Lubbock to the north, and San Angelo to the south. Big Spring was established as the county seat of Howard County in 1882 and is also the largest city in that county. Big Spring apartments for rent comparison page shows most up to date rent information on Big Spring apartments and houses. Rent information is obtained from multiple rental sources but we cannot guarantee their accuracy.